Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 2C isoform A
Ligand
BDBM82369
Substrate
n/a
Ki
5250±n/a nM
Comments
PDSP_1953
Citation
 Mos, J; Van Hest, A; Van Drimmelen, M; Herremans, AH; Olivier, B The putative 5-HT1A receptor antagonist DU125530 blocks the discriminative stimulus of the 5-HT1A receptor agonist flesinoxan in pigeons. Eur J Pharmacol 325:145-53 (1997) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 2C isoform A
Synonyms:
5-HT2C | HTR2C
Type:
Enzyme Catalytic Domain
Mol. Mass.:
45544.61
Organism:
pigeon
Description:
5-HT2C HTR2C pigeon::A0A1V4KYG9
Residue:
405
Sequence:
MCRQLQRASFPEHRCSLSRKKNGGPGNQLEIARSPFAQGCCNLTLNQSLPTSDPLNASEKGEVSRMSVREKNWPALLILVVILLTIGGNILVIMAVSLEKKLQNATNFFLMSLAVADMLVGILVMPVSLITVLYDYAWPLPKQLCPIWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAAVWTISIGISMPIPVMGLQDDSRVFVNGTCVLNDENFVLIGSFMAFFIPLIIMVITYCLTIQVLQRQATVFMCGEVPRQRRSSVNCLKKENNTENISMLHNHEGASHLNSPVNKEAVLFRKGTMQSINNERRASKVLGIVFFLFLIMWCPFFITNVMSVLCKEACDKDLLSELLDVFVWVGRLQFPERRWGMKFWCGFVILTGITCTLGEV
  
Inhibitor
Name:
BDBM82369
Synonyms:
CAS_133025-23-7 | WAY 100,135 | WAY 100135
Type:
Small organic molecule
Emp. Form.:
C24H33N3O2
Mol. Mass.:
395.5377
SMILES:
COc1ccccc1N1CCN(C[C@@H](C(=O)NC(C)(C)C)c2ccccc2)CC1 |r|
Structure:
Search PDB for entries with ligand similarity: