Reaction Details
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Report a problem with these dataTarget
Alpha-1A adrenergic receptor
Ligand
BDBM82517
Substrate
n/a
Ki
0.7±n/a nM
Comments
PDSP_1289
Citation
Mos, J; Van Hest, A; Van Drimmelen, M; Herremans, AH; Olivier, B The putative 5-HT1A receptor antagonist DU125530 blocks the discriminative stimulus of the 5-HT1A receptor agonist flesinoxan in pigeons. Eur J Pharmacol 325:145-53 (1997) [PubMed] Article More Info.:
Target
Name:
Alpha-1A adrenergic receptor
Synonyms:
adrenergic Alpha1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50699.64
Organism:
pigeon
Description:
adrenergic Alpha1 0 pigeon::A0A1V4KJJ8
Residue:
464
Sequence:
MAFLPGNSSDCSNCTHSVGPVNISKAILLGVILGGLIVFGVLGNILVILSVACHRHLQSVTHYYIINLAVADLLLTSTVLPFSATMEILGYWAFGRIFCNIWAAVDVLCCTASIMSLCIISIDRYIGVSYPLRYPSIVTEKRGLLALLCVWALSLVISIGPLFGWKEPAPEDETICQITEEPGYVLFSALGSFYLPLTIILVMYCRVYVVAKRENKGLSSGLKTERSHSEQVTLRIHRKNAPGASGSASNPKSKHHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFVVMPLGSFFPAVKPPDTLFKITFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRVQCLPRKQAAKKQSPSFNLNHPASPSTESSRGVVRIPVGSGETFYKISKSDGVCEWKIFSAVQSMPAKTAVSKDCTAAKVKSKGFLQECCCAGTSGNRGHENCKVPTIKIHTISLSESGEDV
Inhibitor
Name:
BDBM82517
Synonyms:
2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-isoindole-1,3-dione | CAS_107966 | CHEMBL126632 | CHEMBL8618 | NAN-190 | NSC_107966
Type:
Small organic molecule
Emp. Form.:
C23H27N3O3
Mol. Mass.:
393.4788
SMILES:
COc1ccccc1N1CCN(CCCCN2C(=O)c3ccccc3C2=O)CC1
Structure:
