Reaction Details
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Alpha-1A adrenergic receptor
Ligand
BDBM82564
Substrate
n/a
Ki
144±n/a nM
Comments
PDSP_1655
Citation
Mos, J; Van Hest, A; Van Drimmelen, M; Herremans, AH; Olivier, B The putative 5-HT1A receptor antagonist DU125530 blocks the discriminative stimulus of the 5-HT1A receptor agonist flesinoxan in pigeons. Eur J Pharmacol 325:145-53 (1997) [PubMed] Article More Info.:
Target
Name:
Alpha-1A adrenergic receptor
Synonyms:
adrenergic Alpha1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50699.64
Organism:
pigeon
Description:
adrenergic Alpha1 0 pigeon::A0A1V4KJJ8
Residue:
464
Sequence:
MAFLPGNSSDCSNCTHSVGPVNISKAILLGVILGGLIVFGVLGNILVILSVACHRHLQSVTHYYIINLAVADLLLTSTVLPFSATMEILGYWAFGRIFCNIWAAVDVLCCTASIMSLCIISIDRYIGVSYPLRYPSIVTEKRGLLALLCVWALSLVISIGPLFGWKEPAPEDETICQITEEPGYVLFSALGSFYLPLTIILVMYCRVYVVAKRENKGLSSGLKTERSHSEQVTLRIHRKNAPGASGSASNPKSKHHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFVVMPLGSFFPAVKPPDTLFKITFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRVQCLPRKQAAKKQSPSFNLNHPASPSTESSRGVVRIPVGSGETFYKISKSDGVCEWKIFSAVQSMPAKTAVSKDCTAAKVKSKGFLQECCCAGTSGNRGHENCKVPTIKIHTISLSESGEDV
Inhibitor
Name:
BDBM82564
Synonyms:
CAS_132787 | NSC_132787 | S 15535
Type:
Small organic molecule
Emp. Form.:
C21H24N2O2
Mol. Mass.:
336.4275
SMILES:
C1C(Cc2ccccc12)N1CCN(CC1)c1cccc2OCCOc12
Structure:
