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Target
D(2) dopamine receptor
Ligand
BDBM82369
Substrate
n/a
Ki
245±n/a nM
Comments
PDSP_1953
Citation
 Mos, J; Van Hest, A; Van Drimmelen, M; Herremans, AH; Olivier, B The putative 5-HT1A receptor antagonist DU125530 blocks the discriminative stimulus of the 5-HT1A receptor agonist flesinoxan in pigeons. Eur J Pharmacol 325:145-53 (1997) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DRD2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
55052.20
Organism:
pigeon
Description:
DOPAMINE D2 DRD2 pigeon::A0A1V4J7Y5
Residue:
487
Sequence:
MQKPEKFLYLPRGAQEEKTREKSASKHQVCRGVKLEPGTLTSMDPLNLSWYSGDIGDRNWSKPLNESGVDQKPQYNYYAMLLTLLIFVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWRFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAVVWVLSFAISCPLLFGLNNTDENECIIANPAFVVYSSIVSFYVPFIVTLLVYVQIYIVLRRRRKRVNTKRSSHGLDSDTQAPLKDKCTHPEDVKLCTVIVKSNGSFQVNKRKVEVESHIEEMEMVSSTSPLEKTTIKPAAPSNHRLVVPIASTQGTNSTLQAPLDSPGKAEKNGHAKETPRIAKVFEIQSMPNGKLRTSLLKAMNRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNMHCDCSIPPAMYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM82369
Synonyms:
CAS_133025-23-7 | WAY 100,135 | WAY 100135
Type:
Small organic molecule
Emp. Form.:
C24H33N3O2
Mol. Mass.:
395.5377
SMILES:
COc1ccccc1N1CCN(C[C@@H](C(=O)NC(C)(C)C)c2ccccc2)CC1 |r|
Structure:
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