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Target
5-hydroxytryptamine receptor 1A
Ligand
BDBM50194429
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_2951
Citation
 Weber, JT; Hayataka, K; O'Connor, MF; Parker, KK Rabbit cerebral cortex 5HT1a receptors. Comp Biochem Physiol C, Pharmacol Toxicol Endocrinol 117:19-24 (1997) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 1A
Synonyms:
5-HT1A | HTR1A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
18528.48
Organism:
RABBIT
Description:
Q9MZ11
Residue:
170
Sequence:
IPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYVPLLLMLVLYGRIFRAARFRIRKTVKKVEKKGADTRFGATPAPQPRKSVNGEPGSRDWRQGVENKGVGLACANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGAASGAPASFERKNERNAEAKRKMALA
  
Inhibitor
Name:
BDBM50194429
Synonyms:
(-)-parthenolide | (1aR,7aS,10aS,10bS,Z)-1a,5-dimethyl-8-methylene-2,3,6,7,7a,8-hexahydro-11-oxa-bicyclo[8.1.0]undeca-1(10),4-dieno[9,8-b]furan-9(1aH,10aH,10bH)-one | (Z)-(1S,2S,4R,11S)-4,8-Dimethyl-12-methylene-3,14-dioxa-tricyclo[9.3.0.0*2,4*]tetradec-7-en-13-one | CHEMBL540445 | PARTHENOLIDE
Type:
Small organic molecule
Emp. Form.:
C15H20O3
Mol. Mass.:
248.3175
SMILES:
C\C1=C\CC[C@@]2(C)O[C@H]2[C@H]2OC(=O)C(=C)[C@@H]2CC1 |r,t:1|
Structure:
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