Reaction Details
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5-hydroxytryptamine receptor 1A
Ligand
BDBM50007406
Substrate
n/a
Ki
130±n/a nM
Comments
PDSP_1808
Citation
Weber, JT; Hayataka, K; O'Connor, MF; Parker, KK Rabbit cerebral cortex 5HT1a receptors. Comp Biochem Physiol C, Pharmacol Toxicol Endocrinol 117:19-24 (1997) [PubMed] Article More Info.:
Target
Name:
5-hydroxytryptamine receptor 1A
Synonyms:
5-HT1A | HTR1A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
18528.48
Organism:
RABBIT
Description:
Q9MZ11
Residue:
170
Sequence:
IPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYVPLLLMLVLYGRIFRAARFRIRKTVKKVEKKGADTRFGATPAPQPRKSVNGEPGSRDWRQGVENKGVGLACANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGAASGAPASFERKNERNAEAKRKMALA
Inhibitor
Name:
BDBM50007406
Synonyms:
1-(3-(trifluoromethyl)phenyl)piperazine | 1-(3-Trifluoromethyl-phenyl)-piperazine | 1-(3-Trifluoromethyl-phenyl)-piperazine(TFMPP) | CHEMBL274866 | TFMPP
Type:
Small organic molecule
Emp. Form.:
C11H13F3N2
Mol. Mass.:
230.2295
SMILES:
FC(F)(F)c1cccc(c1)N1CCNCC1
Structure:
