| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Dopamine receptors; D2 & D4 |
|---|
| Ligand | BDBM81774 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 200±n/a nM |
|---|
| Comments | PDSP_1785 |
|---|
| Citation |  Seeman, P; Tallerico, T Antipsychotic drugs which elicit little or no parkinsonism bind more loosely than dopamine to brain D2 receptors, yet occupy high levels of these receptors. Mol Psychiatry3:123-34 (1998) [PubMed] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Dopamine receptors; D2 & D4 |
|---|
| Name: | D2-like dopamine receptor |
|---|
| Synonyms: | D(2C) dopamine receptor | D(4) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | Dopamine D4 receptor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 48373.19 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P21917 |
|---|
| Residue: | 467 |
|---|
| Sequence: | MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPGLPPDPCGPDCAPPAPG
LPQDPCGPDCAPPAPGLPRGPCGPDCAPPAPGLPQDPCGPDCAPPAPGLPPDPCGSNCAP
PDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALC
PACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
|
|
|
|---|
| BDBM81774 |
|---|
| Name | BDBM81774 |
|---|
| Synonyms: | CAS_15676-16-1 | SULPIRIDE,(+) | Sulpiride-S | Sulpiride-l |
|---|
| Type | n/a |
|---|
| Emp. Form. | C15H23N3O4S |
|---|
| Mol. Mass. | 341.426 |
|---|
| SMILES | CCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O |r| |
|---|
| Structure | 
|
|---|
| n/a |
|---|
Search and Browse
