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TargetDihydroorotase (DHO)
LigandBDBM85254
Substrate/Competitorn/a
Meas. Tech.Inhibition Assay
pH9±0
Ki 440000000±0 nM
Citation Li, YRaushel, FM Inhibitors designed for the active site of dihydroorotase. Bioorg Chem33:470-83 (2005) [PubMed]  Article
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Dihydroorotase (DHO)
Name:Dihydroorotase (DHO)
Synonyms:n/a
Type:Enzyme
Mol. Mass.:38823.92
Organism:Escherichia coli
Description:P05020
Residue:348
Sequence:
MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYR
QRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSI
DAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHIT
TKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVA
SGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNG
PQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
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  Blast E-value cutoff:
BDBM85254
NameBDBM85254
Synonyms:4,6-dioxo-piperidine-2-carboxylic acid, 3
TypeSmall organic molecule
Emp. Form.C6H6NO4
Mol. Mass.156.1167
SMILES[O-]C(=O)[C@@H]1CC(=O)CC(=O)N1 |r|
Structure
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n/a