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Target
Prostaglandin E2 receptor EP3 subtype
Ligand
BDBM85178
Substrate
n/a
Ki
25±n/a nM
Comments
PDSP_1237
Citation
 Sharif, NA; Xu, SX; Williams, GW; Crider, JY; Griffin, BW; Davis, TL Pharmacology of [3H]prostaglandin E1/[3H]prostaglandin E2 and [3H]prostaglandin F2alpha binding to EP3 and FP prostaglandin receptor binding sites in bovine corpus luteum: characterization and correlation with functional data. J Pharmacol Exp Ther 286:1094-102 (1998) [PubMed] 
Target
Name:
Prostaglandin E2 receptor EP3 subtype
Synonyms:
PE2R3_BOVIN | PTGER3 | Prostaglandin E3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46379.75
Organism:
BOVINE
Description:
Prostaglandin E3 PTGER3 BOVINE::P34979
Residue:
417
Sequence:
MKATRDHASAPFCTRFNHSDPGIWAAERAVEAPNNLTLPPEPSEDCGSVSVAFSMTMMITGFVGNALAITLVSKSYRRREGKRKKSFLLCIGWLALTDMVGQLLTSPVVIVLYLSHQRWEQLDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALATRAPHWYSSHMKTSVTRAVLLGVWLAVLAFALLPVLGVGQYTIQWPGTWCFISTGPGGNGTNSRQNWGNVFFASAFAILGLSALVVTFACNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNHTSVEHCKTYTENQDECNFFLIAVRLASLNQILDPWVYLLLRKILLQKFCQLLKGHSYGLDTEGGTENKDKEMKENLYISNLSRFFILLGHFTEARRGRGHIYLHTLEHQ
  
Inhibitor
Name:
BDBM85178
Synonyms:
CAS_59122-46-2 | MISOPROSTOL | MISOPROSTOL (Methyl Ester) | NSC_5282381
Type:
Small organic molecule
Emp. Form.:
C22H38O5
Mol. Mass.:
382.5341
SMILES:
CCCCC(C)(O)CC=CC1C(O)CC(=O)C1CCCCCCC(=O)OC |w:8.7|
Structure:
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