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Target
Prostaglandin F2-alpha receptor
Ligand
BDBM50106547
Substrate
n/a
Ki
22±n/a nM
Comments
PDSP_1468
Citation
 Sharif, NA; Xu, SX; Williams, GW; Crider, JY; Griffin, BW; Davis, TL Pharmacology of [3H]prostaglandin E1/[3H]prostaglandin E2 and [3H]prostaglandin F2alpha binding to EP3 and FP prostaglandin receptor binding sites in bovine corpus luteum: characterization and correlation with functional data. J Pharmacol Exp Ther 286:1094-102 (1998) [PubMed] 
Target
Name:
Prostaglandin F2-alpha receptor
Synonyms:
PF2R_BOVIN | PGF receptor | PGF2 alpha receptor | PTGFR | ProstaglandinF2Alpha | Prostanoid FP receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41044.75
Organism:
BOVINE
Description:
ProstaglandinF2Alpha PTGFR BOVINE::P37289
Residue:
362
Sequence:
MSTNSSIQPVSPESELLSNTTCQLEEDLSISFSIIFMTVGILSNSLAIAILMKAYQRFRQKYKSSFLLLASALVITDFFGHLINGTIAVFVYASDKDWIYFDKSNILCSIFGICMVFSGLCPLFLGSLMAIERCIGVTKPIFHSTKITTKHVKMMLSGVCFFAVFVALLPILGHRDYKIQASRTWCFYKTDEIKDWEDRFYLLLFAFLGLLALGISFVCNAITGISLLKVKFRSQQHRQGRSHHFEMVIQLLGIMCVSCICWSPFLVTMASIGMNIQDFKDSCERTLFTLRMATWNQILDPWVYILLRKAVLRNLYVCTRRCCGVHVISLHVWELSSIKDSLKVAAISDLPVTEKVTQQTST
  
Inhibitor
Name:
BDBM50106547
Synonyms:
7-[3,5-Dihydroxy-2-(3-hydroxy-4-phenoxy-but-1-enyl)-cyclopentyl]-hept-5-enoic acid | CHEMBL334398 | PGF2Alpha,16-Phenoxy
Type:
Small organic molecule
Emp. Form.:
C22H30O6
Mol. Mass.:
390.47
SMILES:
O[C@@H](COc1ccccc1)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
Structure:
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