Reaction Details
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Report a problem with these dataTarget
Muscarinic acetylcholine receptor M4
Ligand
BDBM50064176
Substrate
n/a
Ki
47.86±n/a nM
Comments
PDSP_1220
Citation
Chelala, JL; Kilani, A; Miller, MJ; Martin, RJ; Ernsberger, P Muscarinic receptor binding sites of the M4 subtype in porcine lung parenchyma. Pharmacol Toxicol 83:200-7 (1998) [PubMed] Article More Info.:
Target
Name:
Muscarinic acetylcholine receptor M4
Synonyms:
CHRM4 | CHRM4 protein | Cholinergic, muscarinic M4
Type:
Enzyme Catalytic Domain
Mol. Mass.:
30028.84
Organism:
bovine
Description:
A6QQE4
Residue:
271
Sequence:
MTVLYVHISLASRSRVHKHRPEGPKEKKAKTLAFLKSPLMKQSVKKPPPPGDTTARGELRNGKLEEAPPPVLPPPPRPMADKDTSNESSSGSATQNTKERPPTELSTTEATTPATPAPPLQPRTLNPASKWSKIQIVTKQTGNECVTAIEIVPATPAGMRPAANVARKFASIARSQVRKKRQMAARERKVTRTIFAILLAFILTWTPYNVMVLVNTFCQSCIPETVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYRNIGTAR
Inhibitor
Name:
BDBM50064176
Synonyms:
CHEMBL27673 | CHEMBL500996 | METHOCTRAMINE | N,N''-Bis-[6-(2-methoxy-benzylamino)-hexyl]-octane-1,8-diamine | N1,N8-bis(6-(2-methoxybenzylamino)hexyl)octane-1,8-diamine
Type:
Small organic molecule
Emp. Form.:
C36H62N4O2
Mol. Mass.:
582.9031
SMILES:
COc1ccccc1CNCCCCCCNCCCCCCCCNCCCCCCNCc1ccccc1OC
Structure:
