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TargetMotilin
LigandBDBM50127141
Substrate/Competitorn/a
Ki 1000±n/a nM
CommentsPDSP_6110
Citation Clark, MJWright, TBertrand, PPBornstein, JCJenkinson, KMVerlinden, MFurness, JB Erythromycin derivatives ABT 229 and GM 611 act on motilin receptors in the rabbit duodenum. Clin Exp Pharmacol Physiol26:242-5 (1999) [PubMed]  Article
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Motilin
Name:Motilin
Synonyms:Promotilin
Type:Enzyme Catalytic Domain
Mol. Mass.:14668.99
Organism:RABBIT
Description:Motilin 0 RABBIT::P27114
Residue:133
Sequence:
MVSRKAVAALLLVHVTAMLASQTEAFVPIFTYSELQRMQERERNRGHKKSLSVQQRSDAA
AAPRPAEPTLEEENGRMQLTAPVEIGMRMNSRQLEKYRAALEAAERAVHPDAPSRPCWPA
GGESGWSGEPSPT
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  Blast E-value cutoff:
BDBM50127141
NameBDBM50127141
Synonyms:(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2R,3S,4R,6S)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione | 11-(4-dimethylamino-3-hydroxy-6-methyltetrahydro-2H-2-pyranyloxy)-3-ethyl-4,5,10-trihydroxy-13-(5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-2-pyranyloxy)-4,6,8,10,12,14-hexamethyl-2-oxacyclotetradecane-1,7-dione | CHEMBL532 | Eryhtromycin A | erythromycin | erythromycin-A
TypeSmall organic molecule
Emp. Form.C37H67NO13
Mol. Mass.733.9268
SMILESCC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@H]2O[C@@H](C)C[C@H]([C@@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O |r|
Structure
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