Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM85392
Substrate
n/a
Ki
7.3±n/a nM
Comments
PDSP_1519
Citation
 Ganapathy, MEPrasad, PDHuang, WSeth, PLeibach, FHGanapathy, V Molecular and ligand-binding characterization of the sigma-receptor in the Jurkat human T lymphocyte cell line. J Pharmacol Exp Ther 289:251-60 (1999) [PubMed] 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25124.85
Organism:
Homo sapiens (Human)
Description:
Q99720
Residue:
223
Sequence:
MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
  
Inhibitor
Name:
BDBM85392
Synonyms:
CAS_131443 | NSC_131443 | PPAP, (-)
Type:
Small organic molecule
Emp. Form.:
C18H23N
Mol. Mass.:
253.3819
SMILES:
CC(Cc1ccccc1)NCCCc1ccccc1
Structure:
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