Reaction Details Report a problem with these data
Target
Norepinephrine transporter
Ligand
BDBM50006786
Substrate
n/a
Ki
778±n/a nM
Comments
PDSP_1631
Citation
 Damaj, MI; Slemmer, JE; Carroll, FI; Martin, BR Pharmacological characterization of nicotine's interaction with cocaine and cocaine analogs. J Pharmacol Exp Ther 289:1229-36 (1999) [PubMed] 
Target
Name:
Norepinephrine transporter
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
2082.45
Organism:
RAT
Description:
Norepinephrine transporter 0 RAT::Q9JIA2
Residue:
19
Sequence:
MLLARMKPQVQPELGGADQ
  
Inhibitor
Name:
BDBM50006786
Synonyms:
3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid isopropyl ester | CHEMBL82093 | RTI-114
Type:
Small organic molecule
Emp. Form.:
C18H24ClNO2
Mol. Mass.:
321.842
SMILES:
CC(C)OC(=O)[C@@H]1C2CC[C@H](C[C@@H]1c1ccc(Cl)cc1)N2C |TLB:21:20:6.12.11:8.9,THB:4:6:20:8.9,13:12:20:8.9|
Structure:
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