Reaction Details Report a problem with these data
Target
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase
Ligand
BDBM85475
Substrate
n/a
Meas. Tech.
Inhibition Assay
pH
5.8±0
Temperature
310.15±0 K
Ki
640000±0 nM
Citation
 Risley, JM; Huang, DH; Kaylor, JJ; Malik, JJ; Xia, YQ Glycosylasparaginase inhibition studies: competitive inhibitors, transition state mimics, noncompetitive inhibitors. J Enzym Inhib 16:269-74 (2001) [PubMed]  Article 
Target
Name:
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase
Synonyms:
AGA | ASPG_HUMAN | Glycosylasparaginase (GA) | N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase
Type:
Enzyme
Mol. Mass.:
37206.38
Organism:
Homo sapiens (Human)
Description:
P20933
Residue:
346
Sequence:
MARKSNLPVLLVPFLLCQALVRCSSPLPLVVNTWPFKNATEAAWRALASGGSALDAVESGCAMCEREQCDGSVGFGGSPDELGETTLDAMIMDGTTMDVGAVGDLRRIKNAIGVARKVLEHTTHTLLVGESATTFAQSMGFINEDLSTTASQALHSDWLARNCQPNYWRNVIPDPSKYCGPYKPPGILKQDIPIHKETEDDRGHDTIGMVVIHKTGHIAAGTSTNGIKFKIHGRVGDSPIPGAGAYADDTAGAAAATGNGDILMRFLPSYQAVEYMRRGEDPTIACQKVISRIQKHFPEFFGAVICANVTGSYGAACNKLSTFTQFSFMVYNSEKNQPTEEKVDCI
  
Inhibitor
Name:
BDBM85475
Synonyms:
GlcNAc-Asn analogue, 11
Type:
Small organic molecule
Emp. Form.:
C10H17ClN2O6
Mol. Mass.:
296.705
SMILES:
CC(=O)NC1C(O)C(O)C(CO)OC1NC(=O)CCl
Structure:
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