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Target
Sodium-dependent noradrenaline transporter
Ligand
BDBM50010859
Substrate
n/a
Ki
93.6±n/a nM
Comments
PDSP_973
Citation
 Paczkowski, FA; Bryan-Lluka, LJ; Pörzgen, P; Brüss, M; Bönisch, H Comparison of the pharmacological properties of cloned rat, human, and bovine norepinephrine transporters. J Pharmacol Exp Ther 290:761-7 (1999) [PubMed] 
Target
Name:
Sodium-dependent noradrenaline transporter
Synonyms:
NORADR | Norepinephrine transporter | SC6A2_BOVIN | SLC6A2 | Sodium-dependent noradrenaline transporter
Type:
Enzyme Catalytic Domain
Mol. Mass.:
68909.35
Organism:
BOVINE
Description:
Norepinephrine transporter 0 BOVINE::P51143
Residue:
615
Sequence:
MLLARMNPQVQPENGGAGPGSEQPPRKRKEVLVVKERNGVQCLLASRDGDEQPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQYNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFSSFTPTLPWTDCGHAWNSPNCTDPKLLNSSVLGNHTKYSKYKFTPAAEFYERGVLHLHESSGIHDIGLPQWQLLLCLIIVVIVLFFSLWKGVKTSGKVVWITATLPYLVLFVLLVHGITLPGASNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSTINCVTSFISGFAIFSILGYMAHEHKVNIEDVATEGAGLVFILYPEAISTLSGSTFWAIVFFIMLLALGIDSSMGGMEAVITGLADDFQVLKRHRKLFTFAVSFGTFLLALFCITKGGIYVLTLLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFKPGLYWRLCWKFVSPAFLLFVVIVSIINFKPLTYDDYIFPLWANWVGWGIAGSSMVLVPAYIVYKFFSTRGSIRERLAYGITPASEHHLVAQRDIRQFQLQHWLAI
  
Inhibitor
Name:
BDBM50010859
Synonyms:
CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE PAMOATE | Imipramin
Type:
Small organic molecule
Emp. Form.:
C19H24N2
Mol. Mass.:
280.4073
SMILES:
CN(C)CCCN1c2ccccc2CCc2ccccc12
Structure:
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