Reaction Details Report a problem with these data
Target
Norepinephrine transporter
Ligand
BDBM22417
Substrate
n/a
Ki
5.74±n/a nM
Comments
PDSP_1330
Citation
 Paczkowski, FA; Bryan-Lluka, LJ; Pörzgen, P; Brüss, M; Bönisch, H Comparison of the pharmacological properties of cloned rat, human, and bovine norepinephrine transporters. J Pharmacol Exp Ther 290:761-7 (1999) [PubMed] 
Target
Name:
Norepinephrine transporter
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
2082.45
Organism:
RAT
Description:
Norepinephrine transporter 0 RAT::Q9JIA2
Residue:
19
Sequence:
MLLARMKPQVQPELGGADQ
  
Inhibitor
Name:
BDBM22417
Synonyms:
3-(2-methoxyphenoxy)-N-methyl-3-phenylpropan-1-amine | CHEMBL295467 | LY 135252 | LY 94939 | LY135252 | LY139602 | Nisoxetine | Nisoxetine Inhibitor | US9944618, Compound ID No. 177 | [3-(2-methoxyphenoxy)-3-phenylpropyl](methyl)amine | [3H]Nisoxetine
Type:
radiolabeled ligand
Emp. Form.:
C17H21NO2
Mol. Mass.:
271.3541
SMILES:
CNCCC(Oc1ccccc1OC)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: