Reaction Details Report a problem with these data
Target
Somatostatin receptor type 4
Ligand
BDBM275918
Substrate
n/a
Meas. Tech.
cAMP Assay
pH
7.4±n/a
Temperature
298.15±n/a K
EC50
21.6±n/a nM
Comments
extracted
Citation
 Mazzaferro, R; Ferrara, M; Giovannini, R; Lingard, I; Rudolf, K Morpholine and 1,4-oxazepane amides as somatostatin receptor subtype 4 (SSTR4) agonists US Patent  US10071974 Publication Date 9/11/2018 
Target
Name:
Somatostatin receptor type 4
Synonyms:
SOMATOSTATIN SST4 | SS-4-R | SS4-R | SS4R | SSR4_HUMAN | SST4R | SSTR4 | Somatostatin receptor type 4 (SSTR4)
Type:
Enzyme
Mol. Mass.:
42015.38
Organism:
Homo sapiens (Human)
Description:
P31391
Residue:
388
Sequence:
MSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLILSYANSCANPILYGFLSDNFRRFFQRVLCLRCCLLEGAGGAEEEPLDYYATALKSKGGAGCMCPPLPCQQEALQPEPGRKRIPLTRTTTF
  
Inhibitor
Name:
BDBM275918
Synonyms:
US10071974, Example 29 | US10577336, Example 29
Type:
Small organic molecule
Emp. Form.:
C16H21FN4O2
Mol. Mass.:
320.3619
SMILES:
Cn1nc(c2c(F)cccc12)C(C)(C)NC(=O)[C@@H]1CNCCO1 |r|
Structure:
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