Reaction Details Report a problem with these data
Target
Somatostatin receptor type 2
Ligand
BDBM275909
Substrate
n/a
Meas. Tech.
Radioligand Binding Assays
Temperature
298.15±n/a K
Ki
9600±n/a nM
Comments
extracted
Citation
 Mazzaferro, R; Ferrara, M; Giovannini, R; Lingard, I; Rudolf, K Morpholine and 1,4-oxazepane amides as somatostatin receptor subtype 4 (SSTR4) agonists US Patent  US10071974 Publication Date 9/11/2018 
Target
Name:
Somatostatin receptor type 2
Synonyms:
SOMATOSTATIN SST2 | SRIF-1 | SS-2-R | SS2-R | SS2R | SSR2_HUMAN | SSTR2 | Somatostatin receptor type 2 (SSTR2)
Type:
Enzyme
Mol. Mass.:
41344.94
Organism:
Homo sapiens (Human)
Description:
P30874
Residue:
369
Sequence:
MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFVVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVLTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI
  
Inhibitor
Name:
BDBM275909
Synonyms:
US10071974, Example 20 | US10071974, Example 21 | US10071974, Example 22 | US10577336, Example 22
Type:
Small organic molecule
Emp. Form.:
C17H24N4O2
Mol. Mass.:
316.3981
SMILES:
Cn1nc(c2ccccc12)C(C)(C)NC(=O)C1CNCCOC1
Structure:
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