Reaction Details Report a problem with these data
Target
Somatostatin receptor type 3
Ligand
BDBM275912
Substrate
n/a
Meas. Tech.
Radioligand Binding Assays
Temperature
298.15±n/a K
Ki
8620±n/a nM
Comments
extracted
Citation
 Mazzaferro, R; Ferrara, M; Giovannini, R; Lingard, I; Rudolf, K Morpholine and 1,4-oxazepane amides as somatostatin receptor subtype 4 (SSTR4) agonists US Patent  US10071974 Publication Date 9/11/2018 
Target
Name:
Somatostatin receptor type 3
Synonyms:
SOMATOSTATIN SST3 | SS-3-R | SS3-R | SS3R | SSR-28 | SSR3_HUMAN | SSTR3 | Somatostatin receptor type 3 (SSTR3)
Type:
Protein
Mol. Mass.:
45855.97
Organism:
Homo sapiens (Human)
Description:
P32745
Residue:
418
Sequence:
MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL
  
Inhibitor
Name:
BDBM275912
Synonyms:
US10071974, Example 23 | US10071974, Example 24 | US10071974, Example 25 | US10577336, Example 25
Type:
Small organic molecule
Emp. Form.:
C17H24N4O2
Mol. Mass.:
316.3981
SMILES:
Cn1nc(c2ccccc12)C(C)(C)NC(=O)C1CNCCCO1
Structure:
Search PDB for entries with ligand similarity: