Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM85617
Substrate
n/a
Ki
380±n/a nM
Comments
PDSP_2889
Citation
 Varani, K; Merighi, S; Gessi, S; Klotz, KN; Leung, E; Baraldi, PG; Cacciari, B; Romagnoli, R; Spalluto, G; Borea, PA [(3)H]MRE 3008F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors. Mol Pharmacol 57:968-75 (2000) [PubMed] 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM85617
Synonyms:
MPC-NECA
Type:
Small organic molecule
Emp. Form.:
C20H22N6O6
Mol. Mass.:
442.4253
SMILES:
COc1ccc(cc1)C(=O)Nc1ncnc2n(cnc12)C1OC(CCC(N)=O)C(O)C1O
Structure:
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