Reaction Details Report a problem with these data
Target
Hrh3 protein
Ligand
BDBM22911
Substrate
n/a
Ki
0.1±n/a nM
Comments
PDSP_968
Citation
 Lovenberg, TW; Pyati, J; Chang, H; Wilson, SJ; Erlander, MG Cloning of rat histamine H(3) receptor reveals distinct species pharmacological profiles. J Pharmacol Exp Ther 293:771-8 (2000) [PubMed] 
Target
Name:
Hrh3 protein
Synonyms:
HISTAMINE H3 | HRH3 | Hrh3 protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37860.96
Organism:
RAT
Description:
Q5PPG3
Residue:
344
Sequence:
MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGRCIPDY
  
Inhibitor
Name:
BDBM22911
Synonyms:
2-(3H-imidazol-4-yl)ethylsulfanylmethanimidamide | CHEMBL19439 | CHEMBL544911 | Imetit | {[2-(1H-imidazol-4-yl)ethyl]sulfanyl}methanimidamide
Type:
Small organic molecule
Emp. Form.:
C6H10N4S
Mol. Mass.:
170.235
SMILES:
NC(=N)SCCc1cnc[nH]1
Structure:
Search PDB for entries with ligand similarity: