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Targetadrenergic Alpha2
LigandBDBM34572
Substrate/Competitorn/a
Ki 478.63±n/a nM
CommentsPDSP_1943
Citation Brink, CBWade, SMNeubig, RR Agonist-directed trafficking of porcine alpha(2A)-adrenergic receptor signaling in Chinese hamster ovary cells: l-isoproterenol selectively activates G(s). J Pharmacol Exp Ther294:539-47 (2000) [PubMed]
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adrenergic Alpha2
Name:adrenergic Alpha2
Synonyms:Alpha-2A adrenergic receptor | adrenergic Alpha2A
Type:Enzyme Catalytic Domain
Mol. Mass.:48998.96
Organism:PIG
Description:adrenergic Alpha2 0 PIG::P18871
Residue:450
Sequence:
MGSLQPEAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLFTVFGNVLVIIAVFT
SRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSS
IVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIVTVWVISAVISFPPLISIEKKAGGGG
QQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAAA
ALPGGAERRPNGLGPERGVGRVGAEAEPLPVQLNGAPGEPAPAGPRDADGLDLEESSSSE
HAERPPGPRRSERGPRAKSKARASQVKPGDSLPRRGPGAPGPGAPATGAGEERGGVAKAS
RWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPPTLFKFFFWFGYCNSS
LNPVIYTIFNHDFRRAFKKILCRGDRKRIV
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  Blast E-value cutoff:
BDBM34572
NameBDBM34572
Synonyms:BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058355 | UK 14,304 | cid_2435
TypeSmall organic molecule
Emp. Form.C11H10BrN5
Mol. Mass.292.135
SMILESBrc1c(NC2=NCCN2)ccc2nccnc12 |t:4|
Structure
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