Reaction Details Report a problem with these data
Target
Gamma-aminobutyric acid receptor subunit rho-3
Ligand
BDBM85712
Substrate
n/a
Ki
150±n/a nM
Comments
PDSP_971
Citation
 Chang, Y; Covey, DF; Weiss, DS Correlation of the apparent affinities and efficacies of gamma-aminobutyric acid(C) receptor agonists. Mol Pharmacol 58:1375-80 (2000) [PubMed]  Article 
Target
Name:
Gamma-aminobutyric acid receptor subunit rho-3
Synonyms:
GABA B rho 1 | GABRR3 | GBRR3_HUMAN | Gamma-aminobutyric acid receptor subunit rho-3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
54281.08
Organism:
Homo sapiens (Human)
Description:
GABA B rho 1 0 HUMAN::A8MPY1
Residue:
467
Sequence:
MVLAFQLVSFTYIWIILKPNVCAASNIKMTHQRCSSSMKQTCKQETRMKKDDSTKARPQKYEQLLHIEDNDFAMRPGFGGSPVPVGIDVHVESIDSISETNMDFTMTFYLRHYWKDERLSFPSTANKSMTFDHRLTRKIWVPDIFFVHSKRSFIHDTTMENIMLRVHPDGNVLLSLRITVSAMCFMDFSRFPLDTQNCSLELESYAYNEDDLMLYWKHGNKSLNTEEHMSLSQFFIEDFSASSGLAFYSSTGWYNRLFINFVLRRHVFFFVLQTYFPAILMVMLSWVSFWIDRRAVPARVSLGITTVLTMSTIITAVSASMPQVSYLKAVDVYLWVSSLFVFLSVIEYAAVNYLTTVEERKQFKKTGKISRMYNIDAVQAMAFDGCYHDSEIDMDQTSLSLNSEDFMRRKSICSPSTDSSRIKRRKSLGGHVGRIILENNHVIDTYSRILFPIVYILFNLFYWGVYV
  
Inhibitor
Name:
BDBM85712
Synonyms:
1H-imidazol-4-ylacetic acid | CAS_645-65-8 | CHEMBL784 | Imidazole-4-acetic acid | NSC_96215
Type:
Small organic molecule
Emp. Form.:
C5H6N2O2
Mol. Mass.:
126.1133
SMILES:
OC(=O)Cc1cnc[nH]1
Structure:
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