Reaction Details
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5-hydroxytryptamine receptor 4
Ligand
BDBM50007871
Substrate
n/a
Ki
158.49±n/a nM
Comments
PDSP_1919
Citation
Bach, T; Syversveen, T; Kvingedal, AM; Krobert, KA; Brattelid, T; Kaumann, AJ; Levy, FO 5HT4(a) and 5-HT4(b) receptors have nearly identical pharmacology and are both expressed in human atrium and ventricle. Naunyn Schmiedebergs Arch Pharmacol 363:146-60 (2001) [PubMed] Article More Info.:
Target
Name:
5-hydroxytryptamine receptor 4
Synonyms:
5-HT-4 | 5-HT4 | 5-HT4S | 5-HT4a | 5-HT4b | 5-HT4c | 5-HT4d | 5-HT4hb | 5-hydroxytryptamine receptor 4 | 5-hydroxytryptamine receptor 4 (5-HT4) | 5HT4R_HUMAN | HTR4 | Serotonin (5-HT) receptor | Serotonin (5-HT3) receptor | Serotonin 4 (5-HT4) receptor | Serotonin Receptor 4
Type:
Enzyme
Mol. Mass.:
43767.54
Organism:
Homo sapiens (Human)
Description:
Q13639
Residue:
388
Sequence:
MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRDAVECGGQWESQCHPPATSPLVAAQPSDT
Inhibitor
Name:
BDBM50007871
Synonyms:
CHEMBL8197 | ICS 205-930 | TROPISETRON
Type:
Small organic molecule
Emp. Form.:
C17H20N2O2
Mol. Mass.:
284.3529
SMILES:
CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 |THB:9:7:1:3.4|
Structure:
