Reaction Details Report a problem with these data
Target
Linoleate 9S-lipoxygenase-4
Ligand
BDBM86024
Substrate
n/a
Meas. Tech.
Inhibition Assay
Temperature
298.15±0 K
IC50
1000000±6000 nM
Citation
 Koukoulitsa, C; Hadjipavlou-Litina, D; Geromichalos, GD; Skaltsa, H Inhibitory effect on soybean lipoxygenase and docking studies of some secondary metabolites, isolated from Origanum vulgare L. ssp. hirtum. J Enzyme Inhib Med Chem 22:99-104 (2007) [PubMed]  Article 
Target
Name:
Linoleate 9S-lipoxygenase-4
Synonyms:
LOX1.5 | LOX4 | LOX4_SOYBN | Lipoxygenase
Type:
Protein
Mol. Mass.:
96526.62
Organism:
Glycine max (Soybean) (Glycine hispida)
Description:
P38417
Residue:
853
Sequence:
MFPFGQKGQKIKGTMVVMQKNVLDINSITSVGGIVDQGLGFIGSAVDALTFAATKISIQLISATKADGGKGKIGKSTNLRGKITLPTLGAGEQAYDVNFEWDSDFGIPGAFYIKNFMQNEFYLKSLILEDIPNHGTIHFVCNSWVYNSKNYKTDRIFFANNTYLPSETPAPLLKYREEELKNVRGDGTGERKEWDRIYDYDVYNDLGNPDSGDKYARPVLGGSALPYPRRERTGRGKTRKDPNSEKPSDFVYLPRDEAFGHLKSSDFLAYGIKSVSQDVLPVLTDAFDGNILSLEFDNFAEVHKLYEGGVTLPTNFLSKIAPIPVIKEIFRTDGEQFLKYPPPKVMQVDKSAWMTDEEFARETIAGLNPNVIKIIEEFPLSSKLDTQAYGDHTCIIAKEHLEPNLGGLTVEQAIQNKKLFILDHHDYLIPYLRKINANTTKTYATRTIFFLKDDGTLTPLAIELSKPHPQGEEYGPVSEVYVPASEGVEAYIWLLAKAYVVVNDACYHQIISHWLSTHAIVEPFVIATNRQLSVVHPIYKLLFPHYRDTMNINSLARKALVNADGIIEKTFLWGRYSMEMSAVIYKDWVFTDQALPNDLVKRGVAVKDPSAPHGVRLLIEDYPYASDGLEIWDAIKSWVQEYVSFYYKSDEELQKDPELQAWWKELVEVGHGDLKDKPWWQKMQTREELVEASAILIWIASALHAAVNFGQYPYGGLILNRPTISRRFMPEKGSPEYDALAKNPEKEFLKTITGKKETLIDLTVIEILSRHASDEFYLGQRDGGDYWTSDAGPLEAFKRFGKKLEEIEKKLIEKNKDETLRNRYGPAKMPYTLLYPSSEEGLTFRGIPNSISI
  
Inhibitor
Name:
BDBM86024
Synonyms:
Lithospermic acid, 3
Type:
Small organic molecule
Emp. Form.:
C36H30O16
Mol. Mass.:
718.6138
SMILES:
OC(=O)[C@@H](Cc1ccc(O)c(O)c1)OC(=O)\C=C\c1ccc(O)c2O[C@@H](C(C(=O)O[C@@H](Cc3ccc(O)c(O)c3)C(O)=O)c12)c1ccc(O)c(O)c1 |r|
Structure:
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