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Target
Linoleate 9S-lipoxygenase-4
Ligand
BDBM86104
Substrate
n/a
Meas. Tech.
Lipoxygenase Inhibition Assay
pH
8±0
Temperature
298.15±0 K
IC50
4.19e+4± 1e+1 nM
Citation
 Ahmad, I; Fatima, I Butyrylcholinesterase, lipoxygenase inhibiting and antifungal alkaloids from Isatis tinctoria. J Enzyme Inhib Med Chem 23:313-6 (2008) [PubMed]  Article 
Target
Name:
Linoleate 9S-lipoxygenase-4
Synonyms:
LOX1.5 | LOX4 | LOX4_SOYBN | Lipoxygenase
Type:
Protein
Mol. Mass.:
96526.62
Organism:
Glycine max (Soybean) (Glycine hispida)
Description:
P38417
Residue:
853
Sequence:
MFPFGQKGQKIKGTMVVMQKNVLDINSITSVGGIVDQGLGFIGSAVDALTFAATKISIQLISATKADGGKGKIGKSTNLRGKITLPTLGAGEQAYDVNFEWDSDFGIPGAFYIKNFMQNEFYLKSLILEDIPNHGTIHFVCNSWVYNSKNYKTDRIFFANNTYLPSETPAPLLKYREEELKNVRGDGTGERKEWDRIYDYDVYNDLGNPDSGDKYARPVLGGSALPYPRRERTGRGKTRKDPNSEKPSDFVYLPRDEAFGHLKSSDFLAYGIKSVSQDVLPVLTDAFDGNILSLEFDNFAEVHKLYEGGVTLPTNFLSKIAPIPVIKEIFRTDGEQFLKYPPPKVMQVDKSAWMTDEEFARETIAGLNPNVIKIIEEFPLSSKLDTQAYGDHTCIIAKEHLEPNLGGLTVEQAIQNKKLFILDHHDYLIPYLRKINANTTKTYATRTIFFLKDDGTLTPLAIELSKPHPQGEEYGPVSEVYVPASEGVEAYIWLLAKAYVVVNDACYHQIISHWLSTHAIVEPFVIATNRQLSVVHPIYKLLFPHYRDTMNINSLARKALVNADGIIEKTFLWGRYSMEMSAVIYKDWVFTDQALPNDLVKRGVAVKDPSAPHGVRLLIEDYPYASDGLEIWDAIKSWVQEYVSFYYKSDEELQKDPELQAWWKELVEVGHGDLKDKPWWQKMQTREELVEASAILIWIASALHAAVNFGQYPYGGLILNRPTISRRFMPEKGSPEYDALAKNPEKEFLKTITGKKETLIDLTVIEILSRHASDEFYLGQRDGGDYWTSDAGPLEAFKRFGKKLEEIEKKLIEKNKDETLRNRYGPAKMPYTLLYPSSEEGLTFRGIPNSISI
  
Inhibitor
Name:
BDBM86104
Synonyms:
Sulfoglucobrassicin, 4
Type:
Small organic molecule
Emp. Form.:
C16H20N2O12S3
Mol. Mass.:
528.531
SMILES:
OCC1OC(SC(Cc2cc3ccccc3n2S(O)(=O)=O)=NOS(O)(=O)=O)C(O)C(O)C1O |w:21.23|
Structure:
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