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Target
Neuronal acetylcholine receptor subunit alpha-6
Ligand
BDBM50038416
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_927
Citation
 Vailati, S; Moretti, M; Longhi, R; Rovati, GE; Clementi, F; Gotti, C Developmental expression of heteromeric nicotinic receptor subtypes in chick retina. Mol Pharmacol 63:1329-37 (2003) [PubMed]  Article 
Target
Name:
Neuronal acetylcholine receptor subunit alpha-6
Synonyms:
ACHA6_CHICK | CHRNA6 | Cholinergic, Nicotinic Alpha6
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57501.33
Organism:
Chick
Description:
Cholinergic, Nicotinic Alpha6 0 Chick::P49581
Residue:
494
Sequence:
MHPKRRLCWCLPASGAWAFMLTSLIADTTACESEERLFHKLFSRYNQFIRPVENVSDPVTVHFELAITQLTNVDEVNQIMETNLWLRHIWNDYKLRRDPREYDGIEFVRVPADKIWKPDIVLYNNAVGDFQVEGKTKALLRYDGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAKIDLLIIGSKVDMNEFWENSEWEIVDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVITVFVLNIHYRTPTTHTMPKWVKTVFLSLLPKVLLMQRPLEQEKKNISKKTKKGSAKTSGKSKHSKHKDNKLHKEQRCCHCDKADDLTSTRRSRLSHQSLKWMAEHTEYSPEVKDVINNVQFIAENMKSQNETKEVEDDWKYVAMVIDRVFLWVFIILCVFGTAGLFIQPLIADT
  
Inhibitor
Name:
BDBM50038416
Synonyms:
(1,6-trimethyl ammonium)hexane; dibromide | CHEMBL100622 | CHEMBL332524 | HEXAMETHONIUM | HEXAMETHONIUM BROMIDE | HEXAMETHONIUM CHLORIDE | Hexamethoniumdibromide | N,N,N,N'',N'',N''-Hexamethyl-1,6-hexanediaminium dibromide | N,N,N,N'',N'',N''-Hexamethylhexane-1,6-diammoniumdibromide
Type:
Small organic molecule
Emp. Form.:
C12H30N2
Mol. Mass.:
202.3789
SMILES:
C[N+](C)(C)CCCCCC[N+](C)(C)C
Structure:
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