Reaction Details
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Gastrin-releasing peptide
Ligand
BDBM86512
Substrate
n/a
Ki
151±n/a nM
Comments
PDSP_3736
Citation
Mantey, SA; Coy, DH; Entsuah, LK; Jensen, RT Development of bombesin analogs with conformationally restricted amino acid substitutions with enhanced selectivity for the orphan receptor human bombesin receptor subtype 3. J Pharmacol Exp Ther 310:1161-70 (2004) [PubMed] Article More Info.:
Target
Name:
Gastrin-releasing peptide
Synonyms:
GRP | GRP_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
16223.81
Organism:
Homo sapiens (Human)
Description:
Gastrin-Releasing peptide 0 HUMAN::P07492
Residue:
148
Sequence:
MRGRELPLVLLALVLCLAPRGRAVPLPAGGGTVLTKMYPRGNHWAVGHLMGKKSTGESSSVSERGSLKQQLREYIRWEEAARNLLGLIEAKENRNHQPPQPKALGNQQPSWDSEDSSNFKDVGSKGKVGRLSAPGSQREGRNPQLNQQ
Inhibitor
Name:
BDBM86512
Synonyms:
CAS_0 | NSC_0 | [D-Tyr6,(R)-Apa11,Phe13,Nle14]Bn(6-14)
Type:
Small organic molecule
Emp. Form.:
C62H81N16O10
Mol. Mass.:
1210.4072
SMILES:
CCCC[C@H](NC(=O)[C@H](Cc1ccccc1)N[N+](=N)[C@H](Cc1cnc[nH]1)NC(=O)C[C@@H](NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](N)Cc1ccc(O)cc1)C(C)C)c1ccccc1)C(N)=O |r|
Structure:
