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Target
cAMP specific phosphodiesterase variant PDE4A-10
Ligand
BDBM86644
Substrate
n/a
Meas. Tech.
In Vitro Enzyme Assay
IC50
2.33e+4±n/a nM
Citation
 Ceyhan, O; Birsoy, K; Hoffman, CS Identification of biologically active PDE11-selective inhibitors using a yeast-based high-throughput screen. Chem Biol 19:155-63 (2012) [PubMed]  Article 
Target
Name:
cAMP specific phosphodiesterase variant PDE4A-10
Synonyms:
Phosphodiesterase 4A10
Type:
Protein
Mol. Mass.:
4891.49
Organism:
Homo sapiens (Human)
Description:
Q9HC30
Residue:
45
Sequence:
MRSGAAPRARPRPPALALPPTGPESLTHFPFSDEDTRRHPPGRSV
  
Inhibitor
Name:
BDBM86644
Synonyms:
BC11-38-2 | US9173884, BC11-38-2
Type:
Small organic molecule
Emp. Form.:
C16H18N2OS2
Mol. Mass.:
318.457
SMILES:
CCC(C)Sc1nc2CCSc2c(=O)n1-c1ccccc1
Structure:
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