Reaction Details Report a problem with these data
Target
Promotilin
Ligand
BDBM86687
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_6111
Citation
 Thielemans, L; Depoortere, I; Perret, J; Robberecht, P; Liu, Y; Thijs, T; Carreras, C; Burgeon, E; Peeters, TL Desensitization of the human motilin receptor by motilides. J Pharmacol Exp Ther 313:1397-405 (2005) [PubMed]  Article 
Target
Name:
Promotilin
Synonyms:
MLN | MOTI_HUMAN | Motilin | Promotilin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12919.83
Organism:
Homo sapiens (Human)
Description:
Motilin 0 HUMAN::P12872
Residue:
115
Sequence:
MVSRKAVAALLVVHVAAMLASQTEAFVPIFTYGELQRMQEKERNKGQKKSLSVWQRSGEEGPVDPAEPIREEENEMIKLTAPLEIGMRMNSRQLEKYPATLEGLLSEMLPQHAAK
  
Inhibitor
Name:
BDBM86687
Synonyms:
ME36
Type:
Small organic molecule
Emp. Form.:
C39H67NO13
Mol. Mass.:
757.9482
SMILES:
CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC2OC(C)CC(C2O)N(C)CC#C)C(C)(O)CC(C)C(=O)C(C)C(O)C1(C)O
Structure:
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