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TargetLipopolysaccharide-induced tumor necrosis factor-alpha factor
LigandBDBM86694
Substrate/Competitorn/a
Ki>10000±n/a nM
CommentsPDSP_4918
Citation Miyata, NSeki, TTanaka, YOmura, TTaniguchi, KDoi, MBandou, KKametani, SSato, MOkuyama, SCambj-Sapunar, LHarder, DRRoman, RJ Beneficial effects of a new 20-hydroxyeicosatetraenoic acid synthesis inhibitor, TS-011 [N-(3-chloro-4-morpholin-4-yl) phenyl-N'-hydroxyimido formamide], on hemorrhagic and ischemic stroke. J Pharmacol Exp Ther314:77-85 (2005) [PubMed]  Article
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Lipopolysaccharide-induced tumor necrosis factor-alpha factor
Name:Lipopolysaccharide-induced tumor necrosis factor-alpha factor
Synonyms:LITAF | LPS-induced TNF-alpha factor | PIG7 | Small integral membrane protein of lysosome/late endosome | TNF-alpha | p53-induced gene 7 protein
Type:Enzyme Catalytic Domain
Mol. Mass.:17106.57
Organism:Homo sapiens (Human)
Description:TNF-alpha 0 HUMAN::Q99732
Residue:161
Sequence:
MSVPGPYQAATGPSSAPSAPPSYEETVAVNSYYPTPPAPMPGPTTGLVTGPDGKGMNPPS
YYTQPAPIPNNNPITVQTVYVQHPITFLDRPIQMCCPSCNKMIVSQLSYNAGALTWLSCG
SLCLLGCIAGCCFIPFCVDALQDVDHYCPNCRALLGTYKRL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM86694
NameBDBM86694
Synonyms:N'-(3-Chloro-4-morpholinophenyl)-N-hydroxyformamidine | TS-011
TypeSmall organic molecule
Emp. Form.C11H14ClN3O2
Mol. Mass.255.701
SMILESONC=Nc1ccc(N2CCOCC2)c(Cl)c1 |w:3.3|
Structure
n/a