Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM86758
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_8528
Citation
 Ohshita, K; Ishiyama, H; Oyanagi, K; Nakata, H; Kobayashi, J Synthesis of hybrid molecules of caffeine and eudistomin D and its effects on adenosine receptors. Bioorg Med Chem 15:3235-40 (2007) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM86758
Synonyms:
2,4-dimethyl-4,9-dihydro-2,4,5,9-tetraaza-fluorene-1,3-dione | CAS_44457469 | NSC_44457469
Type:
Small organic molecule
Emp. Form.:
C11H12N4O2
Mol. Mass.:
232.2386
SMILES:
CN1C2C(Nc3cnccc23)C(=O)N(C)C1=O
Structure:
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