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Target
Phospholipase D2
Ligand
BDBM87152
Substrate
n/a
Meas. Tech.
Cellular PLD2 concentration response
IC50
250±n/a nM
Citation
 PubChem, PC Cellular PLD2 concentration response PubChem Bioassay (2011)[AID] 
Target
Name:
Phospholipase D2
Synonyms:
PLD2 | PLD2_HUMAN | Phospholipase D2 | Phospholipase D2 (PLD2) | phospholipase D2 isoform PLD2A
Type:
Protein
Mol. Mass.:
106002.47
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
933
Sequence:
MTATPESLFPTGDELDSSQLQMESDEVDTLKEGEDPADRMHPFLAIYELQSLKVHPLVFAPGVPVTAQVVGTERYTSGSKVGTCTLYSVRLTHGDFSWTTKKKYRHFQELHRDLLRHKVLMSLLPLARFAVAYSPARDAGNREMPSLPRAGPEGSTRHAASKQKYLENYLNRLLTMSFYRNYHAMTEFLEVSQLSFIPDLGRKGLEGMIRKRSGGHRVPGLTCCGRDQVCYRWSKRWLVVKDSFLLYMCLETGAISFVQLFDPGFEVQVGKRSTEARHGVRIDTSHRSLILKCSSYRQARWWAQEITELAQGPGRDFLQLHRHDSYAPPRPGTLARWFVNGAGYFAAVADAILRAQEEIFITDWWLSPEVYLKRPAHSDDWRLDIMLKRKAEEGVRVSILLFKEVELALGINSGYSKRALMLLHPNIKVMRHPDQVTLWAHHEKLLVVDQVVAFLGGLDLAYGRWDDLHYRLTDLGDSSESAASQPPTPRPDSPATPDLSHNQFFWLGKDYSNLITKDWVQLDRPFEDFIDRETTPRMPWRDVGVVVHGLPARDLARHFIQRWNFTKTTKAKYKTPTYPYLLPKSTSTANQLPFTLPGGQCTTVQVLRSVDRWSAGTLENSILNAYLHTIRESQHFLYIENQFFISCSDGRTVLNKVGDEIVDRILKAHKQGWCYRVYVLLPLLPGFEGDISTGGGNSIQAILHFTYRTLCRGEYSILHRLKAAMGTAWRDYISICGLRTHGELGGHPVSELIYIHSKVLIADDRTVIIGSANINDRSLLGKRDSELAVLIEDTETEPSLMNGAEYQAGRFALSLRKHCFGVILGANTRPDLDLRDPICDDFFQLWQDMAESNANIYEQIFRCLPSNATRSLRTLREYVAVEPLATVSPPLARSELTQVQGHLVHFPLKFLEDESLLPPLGSKEGMIPLEVWT
  
Inhibitor
Name:
BDBM87152
Synonyms:
N-[(1S)-1-[(4-keto-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)methyl]-2-methyl-propyl]quinoline-3-carboxamide;2,2,2-trifluoroacetic acid | N-[(2S)-3-methyl-1-(4-oxidanylidene-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)butan-2-yl]quinoline-3-carboxamide;2,2,2-tris(fluoranyl)ethanoic acid | N-[(2S)-3-methyl-1-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)butan-2-yl]-3-quinolinecarboxamide;2,2,2-trifluoroacetic acid | N-[(2S)-3-methyl-1-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)butan-2-yl]quinoline-3-carboxamide;2,2,2-trifluoroacetic acid | VU0404351-1 | cid_53469944
Type:
Small organic molecule
Emp. Form.:
C28H33N5O2
Mol. Mass.:
471.5939
SMILES:
CC(C)[C@@H](CN1CCC2(CC1)N(CNC2=O)c1ccccc1)NC(=O)c1cnc2ccccc2c1
Structure:
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