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Target
Phospholipase D1
Ligand
BDBM87143
Substrate
n/a
Meas. Tech.
Cellular PLD1 concentration response
IC50
20000±n/a nM
Citation
 PubChem, PC Cellular PLD1 concentration response PubChem Bioassay (2011)[AID] 
Target
Name:
Phospholipase D1
Synonyms:
Choline phosphatase 1 | PLD 1 | PLD1 | PLD1_HUMAN | Phosphatidylcholine-hydrolyzing phospholipase D1 | Phospholipase D (PLD) | Phospholipase D1 | Phospholipase D1 (PLD1) | Phospholipase D2 (PLD2) | hPLD1
Type:
Protein
Mol. Mass.:
124219.92
Organism:
Homo sapiens (Human)
Description:
Q13393
Residue:
1074
Sequence:
MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSAIYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKFKHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRRKQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNCCGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRIDNLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKGYFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLYKEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGIDLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKSIDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTSSYFNHYRSHHNLIHGLKPHFKLFHPSSESEQGLTRPHADTGSIRSLQTGVGELHGETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLLPKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIENQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVYVVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCFRVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFINKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPMEVWT
  
Inhibitor
Name:
BDBM87143
Synonyms:
1-[2-(2-naphthoylamino)ethyl]-N-[2-(2-pyridyl)ethyl]isonipecotamide;2,2,2-trifluoroacetic acid | 1-[2-(naphthalen-2-ylcarbonylamino)ethyl]-N-(2-pyridin-2-ylethyl)piperidine-4-carboxamide;2,2,2-tris(fluoranyl)ethanoic acid | 1-[2-(naphthalene-2-carbonylamino)ethyl]-N-(2-pyridin-2-ylethyl)piperidine-4-carboxamide;2,2,2-trifluoroacetic acid | 1-[2-[[2-naphthalenyl(oxo)methyl]amino]ethyl]-N-[2-(2-pyridinyl)ethyl]-4-piperidinecarboxamide;2,2,2-trifluoroacetic acid | VU0405258-1 | cid_53469915
Type:
Small organic molecule
Emp. Form.:
C26H30N4O2
Mol. Mass.:
430.542
SMILES:
O=C(NCCc1ccccn1)C1CCN(CCNC(=O)c2ccc3ccccc3c2)CC1
Structure:
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