Reaction Details Report a problem with these data
Target
Tegument protein VP16
Ligand
BDBM87259
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3)
IC50
7297±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) PubChem Bioassay (2012)[AID] 
Target
Name:
Tegument protein VP16
Synonyms:
Alpha trans-inducing protein (VP16) | VP16_HHV11 | transactivating tegument protein VP16
Type:
PROTEIN
Mol. Mass.:
54325.13
Organism:
Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1)
Description:
EBI_100271
Residue:
490
Sequence:
MDLLVDELFADMNADGASPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAALFNRLLDDLGFSAGPALCTMLDTWNEDLFSALPTNADLYRECKFLSTLPSDVVEWGDAYVPERTQIDIRAHGDVAFPTLPATRDGLGLYYEALSRFFHAELRAREESYRTVLANFCSALYRYLRASVRQLHRQAHMRGRDRDLGEMLRATIADRYYRETARLARVLFLHLYLFLTREILWAAYAEQMMRPDLFDCLCCDLESWRQLAGLFQPFMFVNGALTVRGVPIEARRLRELNHIREHLNLPLVRSAATEEPGAPLTTPPTLHGNQARASGYFMVLIRAKLDSYSSFTTSPSEAVMREHAYSRARTKNNYGSTIEGLLDLPDDDAPEEAGLAAPRLSFLPAGHTRRLSTAPPTDVSLGDELHLDGEDVAMAHADALDDFDLDMLGDGDSPGPGFTPHDSAPYGALDMADFEFEQMFTDALGIDEYGG
  
Inhibitor
Name:
BDBM87259
Synonyms:
1-(6-Allyloxy-7-methyl-6H-2-oxa-1,3,6-triaza-as-indacen-8-yl)-ethanone | 1-(6-allyloxy-7-methyl-pyrrolo[2,3-g][2,1,3]benzoxadiazol-8-yl)ethanone | 1-(7-methyl-6-prop-2-enoxy-8-pyrrolo[2,3-g][2,1,3]benzoxadiazolyl)ethanone | 1-(7-methyl-6-prop-2-enoxy-pyrrolo[2,3-g][2,1,3]benzoxadiazol-8-yl)ethanone | 1-(7-methyl-6-prop-2-enoxypyrrolo[2,3-g][2,1,3]benzoxadiazol-8-yl)ethanone | MLS000526854 | SMR000117328 | cid_2268220
Type:
Small organic molecule
Emp. Form.:
C14H13N3O3
Mol. Mass.:
271.2713
SMILES:
CC(=O)c1c(C)n(OCC=C)c2ccc3nonc3c12
Structure:
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