Reaction Details Report a problem with these data
Target
V-type proton ATPase subunit c'
Ligand
BDBM87567
Substrate
n/a
Meas. Tech.
Dose Response of Small Molecules that Regulate V-ATPase Proton Transport in Yeast using pHLuorin, Cherry Pick 2
EC50
3644±n/a nM
Citation
 PubChem, PC Dose Response of Small Molecules that Regulate V-ATPase Proton Transport in Yeast using pHLuorin, Cherry Pick 2 PubChem Bioassay (2012)[AID] 
Target
Name:
V-type proton ATPase subunit c'
Synonyms:
CLS9 | TFP3 | VATL2_YEAST | VMA11 | Vma11p
Type:
Enzyme Catalytic Domain
Mol. Mass.:
17039.28
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_6325022
Residue:
164
Sequence:
MSTQLASNIYAPLYAPFFGFAGCAAAMVLSCLGAAIGTAKSGIGIAGIGTFKPELIMKSLIPVVMSGILAIYGLVVAVLIAGNLSPTEDYTLFNGFMHLSCGLCVGFACLSSGYAIGMVGDVGVRKYMHQPRLFVGIVLILIFSEVLGLYGMIVALILNTRGSE
  
Inhibitor
Name:
BDBM87567
Synonyms:
MLS001234266 | SMR000811639 | [4-(6-fluoranyl-1,3-benzothiazol-2-yl)piperazin-1-yl]-(5-nitrofuran-2-yl)methanone | [4-(6-fluoro-1,3-benzothiazol-2-yl)-1-piperazinyl]-(5-nitro-2-furanyl)methanone | [4-(6-fluoro-1,3-benzothiazol-2-yl)piperazin-1-yl]-(5-nitrofuran-2-yl)methanone | [4-(6-fluoro-1,3-benzothiazol-2-yl)piperazino]-(5-nitro-2-furyl)methanone | cid_7539130
Type:
Small organic molecule
Emp. Form.:
C16H13FN4O4S
Mol. Mass.:
376.362
SMILES:
[O-][N+](=O)c1ccc(o1)C(=O)N1CCN(CC1)c1nc2ccc(F)cc2s1
Structure:
Search PDB for entries with ligand similarity: