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Target
Melanocortin receptor 4
Ligand
BDBM88443
Substrate
n/a
Meas. Tech.
Luminescence-based cell-based high throughput dose response assay for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>9913±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay for biased ligands (agonists) of the melanocortin 4 receptor (MC4R) PubChem Bioassay (2012)[AID] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM88443
Synonyms:
1-(1-benzyl-4-piperidyl)-3-(4-sec-butylphenyl)thiourea | 1-(1-benzylpiperidin-4-yl)-3-(4-butan-2-ylphenyl)thiourea | 1-(4-butan-2-ylphenyl)-3-[1-(phenylmethyl)-4-piperidinyl]thiourea | 1-(4-butan-2-ylphenyl)-3-[1-(phenylmethyl)piperidin-4-yl]thiourea | MLS000581437 | N-(1-benzyl-4-piperidinyl)-N'-(4-sec-butylphenyl)thiourea | SMR000200062 | cid_2957625
Type:
Small organic molecule
Emp. Form.:
C23H31N3S
Mol. Mass.:
381.577
SMILES:
CCC(C)c1ccc(NC(=S)NC2CCN(Cc3ccccc3)CC2)cc1
Structure:
Search PDB for entries with ligand similarity: