Reaction Details Report a problem with these data
Target
Melanocortin receptor 4
Ligand
BDBM88475
Substrate
n/a
Meas. Tech.
Luminescence-based cell-based high throughput dose response assay for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>89209±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay for biased ligands (agonists) of the melanocortin 4 receptor (MC4R) PubChem Bioassay (2012)[AID] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM88475
Synonyms:
MLS001007754 | N-[4-[2-(phenylcarbamoylamino)-1,3-thiazol-4-yl]phenyl]acetamide | N-[4-[2-(phenylcarbamoylamino)-1,3-thiazol-4-yl]phenyl]ethanamide | N-[4-[2-(phenylcarbamoylamino)thiazol-4-yl]phenyl]acetamide | N-[4-[2-[[anilino(oxo)methyl]amino]-4-thiazolyl]phenyl]acetamide | SMR000384878 | cid_2554360
Type:
Small organic molecule
Emp. Form.:
C18H16N4O2S
Mol. Mass.:
352.41
SMILES:
CC(=O)Nc1ccc(cc1)-c1csc(NC(=O)Nc2ccccc2)n1
Structure:
Search PDB for entries with ligand similarity: