Reaction Details Report a problem with these data
Target
Delta-type opioid receptor
Ligand
BDBM34677
Substrate
n/a
Meas. Tech.
Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>64567±n/a nM
Citation
PubChem, PC Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R): Luminescence-based cell-based high throughput dose response assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors PubChem Bioassay (2012)[AID]
More Info.:
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
Inhibitor
Name:
BDBM34677
Synonyms:
3-(4-methylbenzoyl)benzo[g][1]benzofuran-4,5-dione | 3-(4-methylbenzoyl)naphtho[1,2-b]furan-4,5-dione | 3-(4-methylphenyl)carbonylbenzo[g][1]benzofuran-4,5-dione | 3-[(4-methylphenyl)-oxomethyl]benzo[g]benzofuran-4,5-dione | 3-p-toluoylbenzo[g]benzofuran-4,5-quinone | MLS000532156 | SMR000137097 | cid_1736341
Type:
Small organic molecule
Emp. Form.:
C20H12O4
Mol. Mass.:
316.3069
SMILES:
Cc1ccc(cc1)C(=O)c1coc-2c1C(=O)C(=O)c1ccccc-21