Reaction Details Report a problem with these data
Target
Delta-type opioid receptor
Ligand
BDBM88428
Substrate
n/a
Meas. Tech.
Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>92499±n/a nM
Citation
PubChem, PC Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R): Luminescence-based cell-based high throughput dose response assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors PubChem Bioassay (2012)[AID]
More Info.:
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
Inhibitor
Name:
BDBM88428
Synonyms:
MLS000523055 | N-(2-furanylmethyl)-8-methyl-4-oxo-N-(3-propan-2-yloxypropyl)-5H-thieno[3,2-c]quinoline-2-carboxamide | N-(2-furfuryl)-N-(3-isopropoxypropyl)-4-keto-8-methyl-5H-thieno[3,2-c]quinoline-2-carboxamide | N-(furan-2-ylmethyl)-8-methyl-4-oxidanylidene-N-(3-propan-2-yloxypropyl)-5H-thieno[3,2-c]quinoline-2-carboxamide | N-(furan-2-ylmethyl)-8-methyl-4-oxo-N-(3-propan-2-yloxypropyl)-5H-thieno[3,2-c]quinoline-2-carboxamide | SMR000128321 | cid_9551548
Type:
Small organic molecule
Emp. Form.:
C24H26N2O4S
Mol. Mass.:
438.539
SMILES:
CC(C)OCCCN(Cc1ccco1)C(=O)c1cc2c(s1)c1cc(C)ccc1[nH]c2=O