Target
Delta-type opioid receptor
Ligand
BDBM88436
Substrate
n/a
Meas. Tech.
Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>92492±n/a nM
Citation
 PubChem, PC Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R): Luminescence-based cell-based high throughput dose response assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors PubChem Bioassay (2012)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM88436
Synonyms:
MLS000573965 | N-[(6-methyl-2-pyridyl)thiocarbamoyl]-2,2-diphenyl-acetamide | N-[(6-methylpyridin-2-yl)carbamothioyl]-2,2-diphenyl-ethanamide | N-[(6-methylpyridin-2-yl)carbamothioyl]-2,2-diphenylacetamide | N-[[(6-methyl-2-pyridinyl)amino]-sulfanylidenemethyl]-2,2-diphenylacetamide | N-{[(6-methyl-2-pyridinyl)amino]carbonothioyl}-2,2-diphenylacetamide | SMR000195552 | cid_1224409
Type:
Small organic molecule
Emp. Form.:
C21H19N3OS
Mol. Mass.:
361.46
SMILES:
Cc1cccc(NC(=S)NC(=O)C(c2ccccc2)c2ccccc2)n1
Structure:
Search PDB for entries with ligand similarity: