Target
Delta-type opioid receptor
Ligand
BDBM79537
Substrate
n/a
Meas. Tech.
Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>92474±n/a nM
Citation
 PubChem, PC Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R): Luminescence-based cell-based high throughput dose response assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors PubChem Bioassay (2012)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM79537
Synonyms:
MLS000595044 | N'-(1H-indol-3-ylmethylene)-2,2-diphenylcyclopropanecarbohydrazide | N'-[(Z)-3-indolylidenemethyl]-2,2-diphenyl-1-cyclopropanecarbohydrazide | N'-[(Z)-indol-3-ylidenemethyl]-2,2-diphenyl-cyclopropane-1-carbohydrazide | N'-[(Z)-indol-3-ylidenemethyl]-2,2-diphenyl-cyclopropanecarbohydrazide | N'-[(Z)-indol-3-ylidenemethyl]-2,2-diphenylcyclopropane-1-carbohydrazide | SMR000184430 | cid_5717454
Type:
Small organic molecule
Emp. Form.:
C25H21N3O
Mol. Mass.:
379.4537
SMILES:
O=C(NN=Cc1c[nH]c2ccccc12)C1CC1(c1ccccc1)c1ccccc1 |w:3.2|
Structure:
Search PDB for entries with ligand similarity: