Target
Delta-type opioid receptor
Ligand
BDBM50213
Substrate
n/a
Meas. Tech.
Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>92455±n/a nM
Citation
 PubChem, PC Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R): Luminescence-based cell-based high throughput dose response assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors PubChem Bioassay (2012)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50213
Synonyms:
3-Hydroxy-naphthalene-2-carboxylic acid (1-benzyl-2-oxo-1,2-dihydro-indol-3-ylidene)-hydrazide | 3-hydroxy-N-[(Z)-[2-oxo-1-(phenylmethyl)-3-indolylidene]amino]-2-naphthalenecarboxamide | 3-oxidanyl-N-[(Z)-[2-oxidanylidene-1-(phenylmethyl)indol-3-ylidene]amino]naphthalene-2-carboxamide | MLS000553595 | N-[(Z)-(1-benzyl-2-keto-indolin-3-ylidene)amino]-3-hydroxy-2-naphthamide | N-[(Z)-(1-benzyl-2-oxoindol-3-ylidene)amino]-3-hydroxynaphthalene-2-carboxamide | SMR000171355 | cid_9591396
Type:
Small organic molecule
Emp. Form.:
C26H19N3O3
Mol. Mass.:
421.4474
SMILES:
Oc1cc2ccccc2cc1C(=O)N\N=C1/C(=O)N(Cc2ccccc2)c2ccccc12
Structure:
Search PDB for entries with ligand similarity: