Target
Delta-type opioid receptor
Ligand
BDBM52442
Substrate
n/a
Meas. Tech.
Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>92448±n/a nM
Citation
 PubChem, PC Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R): Luminescence-based cell-based high throughput dose response assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors PubChem Bioassay (2012)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM52442
Synonyms:
2-[2-[(3-amino-7-methyl-thieno[2,3-b]quinoline-2-carbonyl)amino]thiazol-4-yl]acetic acid ethyl ester | 2-[2-[[(3-amino-7-methyl-2-thieno[2,3-b]quinolinyl)-oxomethyl]amino]-4-thiazolyl]acetic acid ethyl ester | MLS000564527 | SMR000172488 | cid_3167478 | ethyl 2-[2-[(3-amino-7-methylthieno[2,3-b]quinoline-2-carbonyl)amino]-1,3-thiazol-4-yl]acetate | ethyl 2-[2-[(3-azanyl-7-methyl-thieno[2,3-b]quinolin-2-yl)carbonylamino]-1,3-thiazol-4-yl]ethanoate | {2-[(3-Amino-7-methyl-thieno[2,3-b]quinoline-2-carbonyl)-amino]-thiazol-4-yl}-acetic acid ethyl ester
Type:
Small organic molecule
Emp. Form.:
C20H18N4O3S2
Mol. Mass.:
426.512
SMILES:
CCOC(=O)Cc1csc(NC(=O)c2sc3nc4cc(C)ccc4cc3c2N)n1
Structure:
Search PDB for entries with ligand similarity: