Target
Delta-type opioid receptor
Ligand
BDBM88463
Substrate
n/a
Meas. Tech.
Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>92462±n/a nM
Citation
 PubChem, PC Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R): Luminescence-based cell-based high throughput dose response assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors PubChem Bioassay (2012)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM88463
Synonyms:
MLS000731927 | SMR000316058 | [1-[(3,5-dimethyl-1H-indol-2-yl)methyl]-3-(3-methoxybenzyl)piperidin-3-yl]methanol | [1-[(3,5-dimethyl-1H-indol-2-yl)methyl]-3-[(3-methoxyphenyl)methyl]-3-piperidinyl]methanol | [1-[(3,5-dimethyl-1H-indol-2-yl)methyl]-3-[(3-methoxyphenyl)methyl]piperidin-3-yl]methanol | [1-[(3,5-dimethyl-1H-indol-2-yl)methyl]-3-m-anisyl-3-piperidyl]methanol | cid_16189221
Type:
Small organic molecule
Emp. Form.:
C25H32N2O2
Mol. Mass.:
392.5338
SMILES:
COc1cccc(CC2(CO)CCCN(Cc3[nH]c4ccc(C)cc4c3C)C2)c1
Structure:
Search PDB for entries with ligand similarity: