Target
Delta-type opioid receptor
Ligand
BDBM50627
Substrate
n/a
Meas. Tech.
Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>92473±n/a nM
Citation
 PubChem, PC Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R): Luminescence-based cell-based high throughput dose response assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors PubChem Bioassay (2012)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50627
Synonyms:
(6E)-2-methoxy-6-[[2-(2-pyridin-3-ylquinazolin-4-yl)hydrazinyl]methylidene]cyclohexa-2,4-dien-1-one | (6E)-2-methoxy-6-[[N'-[2-(3-pyridyl)quinazolin-4-yl]hydrazino]methylene]cyclohexa-2,4-dien-1-one | (6E)-2-methoxy-6-[[[2-(3-pyridinyl)-4-quinazolinyl]hydrazo]methylidene]-1-cyclohexa-2,4-dienone | 2-Methoxy-6-[(2-pyridin-3-yl-quinazolin-4-yl)-hydrazonomethyl]-phenol | MLS000777524 | SMR000413918 | cid_5515318
Type:
Small organic molecule
Emp. Form.:
C21H17N5O2
Mol. Mass.:
371.392
SMILES:
COc1cccc(CN=Nc2nc(nc3ccccc23)-c2cccnc2)c1O |w:9.9|
Structure:
Search PDB for entries with ligand similarity: