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Target
Delta-type opioid receptor
Ligand
BDBM78962
Substrate
n/a
Meas. Tech.
Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>10280±n/a nM
Citation
 PubChem, PC Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R): Luminescence-based cell-based high throughput dose response assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors PubChem Bioassay (2012)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM78962
Synonyms:
2-(6-chloranyl-4-phenyl-quinazolin-2-yl)guanidine;hydrochloride | 2-(6-chloro-4-phenyl-2-quinazolinyl)guanidine;hydrochloride | 2-(6-chloro-4-phenyl-quinazolin-2-yl)guanidine;hydrochloride | 2-(6-chloro-4-phenylquinazolin-2-yl)guanidine;hydrochloride | MLS001206456 | N-(6-Chloro-4-phenyl-quinazolin-2-yl)-guanidine | SMR000518356 | cid_24746808
Type:
Small organic molecule
Emp. Form.:
C15H12ClN5
Mol. Mass.:
297.742
SMILES:
[#7]\[#6](-[#7])=[#7]\c1nc(-c2ccccc2)c2cc(Cl)ccc2n1
Structure:
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