Target
Delta-type opioid receptor
Ligand
BDBM78963
Substrate
n/a
Meas. Tech.
Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>92401±n/a nM
Citation
 PubChem, PC Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R): Luminescence-based cell-based high throughput dose response assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors PubChem Bioassay (2012)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM78963
Synonyms:
MLS001205948 | N-(4,5-Dihydro-1H-imidazol-2-yl)-N'-[1-(4-hexyloxy-phenyl)-ethylidene]-hydrazine | N-[1-(4-hexoxyphenyl)ethylideneamino]-4,5-dihydro-1H-imidazol-2-amine | SMR000513357 | [(E)-1-(4-hexoxyphenyl)ethylideneamino]-(2-imidazolin-2-yl)amine | [1-(4-hexoxyphenyl)ethylideneamino]-(2-imidazolin-2-yl)amine | cid_3098371
Type:
Small organic molecule
Emp. Form.:
C17H26N4O
Mol. Mass.:
302.4145
SMILES:
CCCCCCOc1ccc(cc1)C(C)=NNC1=NCCN1 |w:15.16,t:18|
Structure:
Search PDB for entries with ligand similarity: