Target
Delta-type opioid receptor
Ligand
BDBM79016
Substrate
n/a
Meas. Tech.
Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>92491±n/a nM
Citation
 PubChem, PC Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R): Luminescence-based cell-based high throughput dose response assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors PubChem Bioassay (2012)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM79016
Synonyms:
(4-amino-6,7-dimethoxy-quinazolin-2-yl)-(3-chloro-4-methyl-phenyl)amine;hydrochloride | 2-N-(3-chloro-4-methylphenyl)-6,7-dimethoxyquinazoline-2,4-diamine;hydrochloride | MLS001199666 | N2-(3-chloranyl-4-methyl-phenyl)-6,7-dimethoxy-quinazoline-2,4-diamine;hydrochloride | N2-(3-chloro-4-methylphenyl)-6,7-dimethoxyquinazoline-2,4-diamine;hydrochloride | N~2~-(3-chloro-4-methylphenyl)-6,7-dimethoxyquinazoline-2,4-diamine | SMR000560136 | cid_24762072
Type:
Small organic molecule
Emp. Form.:
C17H17ClN4O2
Mol. Mass.:
344.795
SMILES:
COc1cc2nc(Nc3ccc(C)c(Cl)c3)nc(N)c2cc1OC
Structure:
Search PDB for entries with ligand similarity: